Zvi Pasman

Department of Chemistry

Illinois College

1101 West College Avenue

Jacksonville IL 62650

Office telephone 217-245-3435; fax 217-245-3358; email zpasman@ic.edu;

Education:

1998-2002: American Cancer Society Post-doctoral fellow. Study of the regulation of intrinsic and Rho-dependent transcription termination in E. coli. Advisor: Peter H. von Hippel, Department of Chemistry and Institute of Molecular Biology, University of Oregon, Eugene, OR.

1991-1997: Duke University, Durham, NC. Ph.D., Departments of Microbiology and Immunology. Dissertation title: Splice site approximation in pre-messenger RNA splicing. Advisor: Mariano A. Garcia-Blanco.

1991: Duke University, Durham,, NC. B.S. Departments of Zoology and Religion.

1985: Herricks Senior High School, Searingtown, NY. Diploma.

Current employment:

2003-present: Assistant Professor of Chemistry, Illinois College, Jacksonville, IL

I. Teaching. Develop courses to meet the mission statements and enhance the departmental offerings of the Departments of Chemistry and Biology. All courses except Advanced Molecular Biology include three weekly hours of laboratory instruction:

General Biochemistry I and II

General Chemistry I and II

General Chemistry I

Chemistry Senior Seminar I and II

Cell and Molecular Biology

Advanced Molecular Biology

II. Research. Maintain a research program involving Illinois College students.

A. Richard Meyerholz, interaction of E. coli transcription termination Rho with active elongation complexes. 2006-07.

Ashley Maul, abnormal expression of growth factors in gray horse melanomas. Summer 2006

Jennifer Sauer, susceptibility of the Athlete’s foot fungus Trychophyton rubrum to anti-fungal drug combination. Summer 2005.

Dustin Swanson, optimal labeling of RNAs in vitro using fluorescent nucleotide analogs. Summer 2004.

III. Service to the College.

A. Service on the following committees:

Illinois College Assessment Committee, 2004-06, chair 2006-present

Grievance committee, 2005/06

Discipline committee, 2004-2006

Athletics committee, 2003/04

Student life committee, 2004/05

Pre-health professions committee, 2004-present

Chemistry search committees, 2003-2006

B. Advising. Advise students interested in careers involving chemistry, biochemistry, and molecular biology. In addition, assist Dr. Elaine Chapman in advising students preparing for health-related careers. Write evaluation letters for students seeking admission to health-related professional schools, graduate training programs, and summer research experiences outside of Illinois College. Become a member and, starting in 2004, attend the meetings of the National Association of Advisors to the Health Professions.

C. Project Kaleidoscope Leadership Initiative (PKAL-LI) team leader. Project kaleidoscope is a national organization whose mission is to promote and enhance college-level education in science, technology, engineering, and mathematics. Participate in the application process to the leadership initiative and, upon acceptance of the College to the program, act as a point person for PKAL-LI in order to facilitate accomplishment of goals related to science, technology, engineering, and mathematics education. Distribute materials for consideration and coordinate discussions of relevant issues at the College. Communicate materials between the College and PKAL. Coordinate travel of College personnel to PKAL seminars and workshops. Promote external funding requests for an academic excellence coordinator in the mathematics and science departments.

D. Literary Society Production Judge, Men’s societies, fall 2003, spring 2004, fall 2004.

Previous employment, research and teaching training:

2002-2003: Visiting Assistant Professor. Teach undergraduate two-semester general chemistry and biochemistry courses. Develop lectures and exams for both courses. Develop and teach a one-semester laboratory course in biochemistry. Instruct laboratory and problem-solving sections of the general chemistry course. Teaching experience at Fort Lewis College, Durango, CO.

2001, 2002: Teaching Assistant. Teaching discussion sections of upper level biochemistry courses. Lead and grade discussions of recent publications in distinct areas of biochemistry. Teaching training with Professors Diane Hawley and Thomas Stevens, University of Oregon, Eugene, OR.

1998-2002: Post-doctorate research. Study of the regulation of intrinsic and Rho-dependent transcription termination in E. coli. Research training in the laboratory of Peter H. von Hippel, Department of Chemistry and Institute of Molecular Biology, University of Oregon, Eugene, OR.

1991-1997: Graduate research. Study of the mechanisms that govern splice site approximation in pre-mRNA splicing. Research training in the laboratory of Mariano A. Garcia Blanco, Department of Microbiology, Duke University, Durham, NC.

1991: Research Technician, Study of the function of Drosophila melanogaster non-chromosome disjunction protein, a microtubule-dependent molecular motor. Research training in the laboratory of Sharyn Endow, Department of Microbiology, Duke University, Durham, NC.

1990: Undergraduate independent research. Study of the effects of secondary sex organs morphology on the sexual fitness of Drosophila melanogaster strains. Research training in the laboratory of Cathy Laurie, Department of Zoology, Duke University, Durham, NC.

1990: Hartford Undergraduate Scholar. Scholarship from the Hartford Foundation for the study of insulin effects on protein expression in tissue-cultured eukaryotic cells. Research training on the laboratory of Richard Levenson, Department of Pathology, Duke University, Durham, NC.

1988-1989: Environmental technician. Detection and remediation of radioactive contaminants in air, soil, and water at RAD Environmental Services, Durham, NC.

1988: Undergraduate research assistant. Study of the effects of high oxygen levels on growth of tissue-cultured human fibroblasts. Research training in the laboratory of Doug Darr, Department of Dermatology, Duke University, Durham, NC.

Publications:

Grieve, S.J., Weizel, S.E., Goodarzi, J.P., Main, L.J., Pasman, Z., and von Hippel, P.H. (2008). Monitoring RNA transcription in real-time by using surface plasmon resonance. Proc. Natl. Acad. Sci. U.S.A. 105:3315-3320.

Pasman, Z., and von Hippel, P.H. (2002). Active Escherichia coli transcription elongation complexes are functionally homogeneous. J. Mol. Biol. 322:505-519.

von Hippel, P.H., and Pasman, Z. (2002). Determining the reaction pathways of transcription complexes. Biophysical Chemistry, 101-102:401-423.

Pasman, Z., and von Hippel, P.H. (2000). Regulation of Rho-dependent transcription termination by NusG is specific to the E. coli elongation complex. Biochemistry 39:5573-5585.

Pasman, Z., Been, M.D., and Garcia-Blanco, M.A. (1996). Exon Circularization in mammalian nuclear extracts. RNA 2:603-610.

Pasman, Z., and Garcia-Blanco, M.A. (1996). The 5' and 3' splice sites come together via a three dimensional diffusion mechanism. Nucl. Acids Res. 24:1638-1645.

Jamison, S.F., Pasman, Z., Wang, J., Will, C., Luhrmann, R., Manley, J.L., and Garcia-Blanco, M.A. (1995). U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements. Nucl. Acids Res. 23:3260-3267.

Presentations:

Meyerholz, R.A. and Pasman, Z. Interactions of E. coli transcription elongation complex with termination factor Rho (abstract). Poster presentation at the 41st Midwest American Chemical Society Meeting, Quincy, IL, October 25-27, 2006.

Maul, A. and Pasman, Z. Grey horse melanoma development, treatment, and prevention. Oral presentation at the Annual Meeting of the United States Equine Eventing Association, St. Louis, MO, December 2006.

Pasman, Z. and von Hippel, P.H. Regulation of Rho-dependent termination by NusG (abstract). Oral presentation at the Post-Initiation Activities of RNA Polymerases meeting, Mountain Lake, VA, October 26-29, 2000.

Pasman, Z. and von Hippel, P.H. Transcription termination activity of NusG is specific to the interaction between Rho and the E. coli elongation complex. Poster presentation at the 44th annual meeting of the Biophysical Society, New Orleans, LA, February 12-16, 2000.

Pasman, Z. and Garcia-Blanco, M.A. Exon circularization by the spliceosome (abstract). Oral presentation at the 1st annual Meeting of the RNA Society, University of Wisconsin-Madison, May 28-June 2, 1996.

Pasman, Z. and Garcia-Blanco, M.A. Mammalian pre-mRNA splice site pairing involves a scanning mechanism (abstract). Poster presentation at the RNA Processing Meeting, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, May 17-21, 1995.

Jamison, S.F., Pasman, Z., Zelano, A., Kohtz, J.D., Luhrmann, R., Manley, J.L., and Garcia- Blanco, M.A. U1 snRNP-ASF/SF2 interactions define the 5' splice site of pre-mRNAs (abstract). Oral presentation at the RNA Processing Meeting of the RNA Society, University of Wisconsin-Madison, May 24-29, 1994.

Grants and Fellowships:

1998-2000: American Cancer Society post-doctoral fellowship for the study of the regulation of transcription by E. coli Rho factor in the laboratory of Peter H. von Hippel, Department of Chemistry and Institute of Molecular Biology, University of Oregon, Eugene, OR.

2000: Biacore-Pharmacia Inc. grant for a presentation at the 44th Annual Meeting of the Biophysical Society, New Orleans, LA, February 12-16, 2000.

1999: National center for Analytical Ultracentrifugation fellowship to attend the Analytical Ultracentrifugation Workshop and Symposium, March 16-19, 1999, University of Connecticut, Storrs, CT.

Personal:

Born April 26, 1967, in Ramat-Gan, Israel.

Emigrated to the U.S. 1984, U.S. citizenship 1992.

April 2008.